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The activation of the LYN kinase plays a role in some cases of imatinib resistance that are not caused by mutations in the amplification of the BCR-ABL gene in patients with chronic myelogenous leukemia. Medscape Medical News
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In a large case-control study, a CALHM1 variant was found to affect calcium permeability and amyloid precursor protein in the hippocampus. Medscape Medical News
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Blood pressure targets in men and women with coronary artery disease or who are at high risk should be 130/80 mm Hg, according to the American Heart Association. Medscape Medical News
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The criteria will help guide clinicians in determining when and how often to use transthoracic and transesophageal echocardiography. Medscape Medical News
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Investigators show that despite advanced age and reduced life expectancy, coronary artery calcium scoring discriminates mortality risk in older patients. Medscape Medical News
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Both cardiovascular and all-cause mortality were increased in individuals with low levels of vitamin D in a new prospective cohort study. Medscape Medical News
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After all of the advances in the hospital management of acute myocardial infarction, there are opportunities for improving outcomes in the postdischarge setting, researchers argue. Medscape Medical News
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The FDA has approved ropinirole extended-release tablets (Requip XL) for the once-daily treatment of Parkinson's disease. Medscape Medical News
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