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Humans express several proteins that breakdown the synthetic chemicals and drugs (collectively known as xenobiotics) that we ingest or are administered. Expression of these proteins is itself regulated by the xenobiotic-sensing proteins PXR and CAR.
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Endocannabinoids are substances produced by several cells in the body that are very similar to compounds found in cannabis plants. They have been implicated in the development of many effects of a high-fat diet, including many risk factors for type
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University of Illinois researchers report this week that chronic exposure to estradiol, the main estrogen in the body, diminishes some cognitive functions. Rats exposed to a steady dose of estradiol were impaired on tasks involving working memory an
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New data, generated in mice by Riko Nishimura and colleagues, at Osaka University Graduate School of Dentistry, Japan, have provided insight into the formation of cartilage, a process that is known as chondrogenesis and that is an important event in
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New insight into the way in which inflammatory cells known as macrophages leave the blood and access sites of injury has been provided by Jane Hoover-Plow and colleagues, at Cleveland Clinic Lerner Research Institute, Cleveland, who studied the proc
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Toxic drugs, toxic system: Sociologist predicts drug disasters, says prescription drug harm growing, drug testing, approval and marketing flaws Americans are likely to be exposed to unacceptable side effects of FDA-approved drugs such as Vioxx in
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The mammoth increase in the United States' prison population since the 1970s is having profound demographic consequences that disproportionately affect black males.
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Onyx M.D. believes it has a remedy — if not the cure — for the upcoming national doctor shortage.
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