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Adding the novel heart-rate-reducing medication to atenolol 50 mg in patients with stable angina improved exercise duration compared with beta-blocker use alone. Ivabradine was also shown to be safe and well tolerated, report investigators. Heartw
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Even maternal blood lead levels less than 10 micrograms per deciliter may raise the risk of prematurity or decreased fetal size even in a select group of low-risk pregnant women. Medscape Medical News
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Propofol infusion syndrome, an irreversible, potentially fatal reaction to prolonged, high-dose infusions of the sedative, can occur in the treatment of refractory status epilepticus. Medscape Medical News
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In a randomized study, early insulin therapy reduced hyperglycemia in very-low-birth-weight infants but increased hypoglycemia, without significant improvements in primary and secondary outcomes. Medscape Medical News
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A new retrospective cohort study shows that beta-blocker use perioperatively in patients undergoing noncardiac surgery should be confined to those at intermediate or high risk for cardiac events. Medscape Medical News
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A randomized trial shows that vitamin K supplementation for 36 months at doses attainable in the diet may reduce progression of insulin resistance in older men. Medscape Medical News
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Patients with preexisting medical conditions are more likely to have new neurological symptoms misdiagnosed, a new study shows. Medscape Medical News
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The FDA has approved revisions to the safety labeling for a fluocinolone acetonide intravitreal implant, levothyroxine sodium tablets, and amlodipine plus valsartan tablets. Medscape Medical News
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