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Researchers have developed a way of directly measuring how efficient drugs are in reaching their targets, which could lead to the development of new and improved drug substances. The study, by researchers at Karolinska Institutet in Sweden, has led
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The drug rofecoxib (Vioxx), an anti-inflammatory drug used for arthritis, was previously taken off the US market because of serious cardiovascular side effects. However, new research has found that the class of drugs known as COX-2 inhibitors may ye
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Present Food and Drug Administration (FDA) regulations prohibit generic drug manufacturers from updating a product's safety labeling quickly. This creates a problematic safety gap, whereby the public is left unaware of potential health risks from th
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New research from Western University unravels a novel means of communication that allows bacteria such as Burkholderia cenocepacia (B. cenocepacia) to resist antibiotic treatment. B. cenocepacia is an environmental bacterium that causes devastating
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Malignant tumours often spread to remote areas of the body. In the majority of cases, metastases formation develops via the blood vascular system. The blood platelets thereby provide invaluable help to the tumour cells in penetrating new organs. Sci
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In a study from Boston University's National Emerging Infectious Diseases Laboratories (NEIDL), researchers have generated a map of the cellular circuitry of Mycobacterium tuberculosis, the causative agent of human tuberculosis (TB). This informatio
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Researchers are striving to understand the different genetic structures that underlie at least a subset of autism spectrum disorders. In cases where the genetic code is in error, did that happen anew in the patient, perhaps through mutation or copyi
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Thousands of sequences that control genes are active in the developing human limb and may have driven the evolution of the human hand and foot, a comparative genomics study led by Yale School of Medicine researchers has found The research, published
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