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Using powerful leading-edge technology, researchers reveal for the first time that the true 3D structures of chromosomes are far removed from the blurry, slightly distorted X-shape many of us are familiar with. They are, in fact, complex and rathe
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Patients who have been mechanically ventilated in intensive care units have long been known to suffer some form of mental impairment as a result. Now, researchers have uncovered a molecular mechanism that may explain why this happens. The study, pub
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Scientists have created a type of nanoparticle that they say can effectively deliver vaccines to the lungs, protecting against numerous infectious diseases. This is according to a study published in Science Translational Medicine. Researchers from t
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Scientists have used a brand new technique for examining individual stem cells to uncover dramatic differences in the gene expression levels - which genes are turned 'up' or 'down' - between apparently identical 'sister' pairs. The research, publish
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Distal renal tubular acidosis (dRTA) develops in response to the loss of acid secretion by α-intercalated cells in the kidney. The inability to remove acid from the body results in low blood potassium levels (hypokalemia), dehydration, and excess c
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Common variable immune deficiency (CVID) is a genetic disease associated with enhanced susceptibility to infection, autoimmunity, and decreased antibody production. Mutations in the tumor necrosis factor receptor superfamily member TACI, are associa
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Individuals with a mutation in the gene encoding a zinc transporter, SLC30A8 have an elevated risk of developing type 2 diabetes. Insulin granules that are released from pancreatic β cells contain high levels of zinc; however, it is not clear why i
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Adult survivors of childhood cancers who underwent certain chemotherapy treatments or kidney surgery had worse kidney function that did not recover over time. Because of this, they may be at higher risk for premature renal failure, according to a st
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