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T-DM1, a successor to trastuzumab, should be the preferred choice for HER2-positive breast cancer that has progressed despite multiple lines of treatment, new research shows. br / iMedscape Medical News/i
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Daclatasvir is the first in a new class of antivirals that block the action of NS5A, a protein which is essential for HCV to replicate. br / iInternational Approvals/i
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The drug would be available in two doses—clopidogrel 75 mg/aspirin 75 mg and clopidogrel 75 mg/aspirin 100 mg—for patients at risk for atherothrombotic events already taking both drugs. br / iHeartwire/i
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There are a number of concerns about screening high-risk Medicare beneficiaries for lung cancer with low-dose CT, says one expert. br / iMedscape Medical News/i
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Another use in a ovarian cancer is recommended for approval in Europe, as is use of regorafenib for gastrointestinal stromal tumors (GIST). br / iInternational Approvals/i
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Obese women who become pregnant are more likely to deliver before 28 weeks of pregnancy, but the association between prepregnancy BMI and risk for preterm birth is complex. br / iMedscape Medical News/i
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European advisors recommend extending the oral anticoagulants marketing authorization to treatment of deep vein thrombosis and pulmonary embolism, plus prevention of their recurrences in adults. br / iHeartwire/i
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The EU’s Committee for Medicinal Products for Human Use has given a positive opinion for marketing of Triumeq, a once-daily combination of the antivirals dolutegravir, abacavir, and lamivudine. br / iInternational Approvals/i
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