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Tested in high-risk CVD patients, heterozygous-FH patients, and patients intolerant to statins, treatment with alirocumab resulted in as large as a 60% reduction in LDL cholesterol from baseline. Some patients even got down to LDLs of 50 mg/dL.
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As the drugs main effect is to lower heart rate, the randomized, placebo-controlled trial questions HR as a treatment target in stable CAD patients without heart failure, researchers say. br / iHeartwire/i
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The ESC downgraded its beta-blocker recommendations in STEMI and NSTEMI patients with no HF, while US guidance still recommends their use out to three years. New data call that into question. br / iHeartwire/i
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Women with a history of severe acne in their teenage years are at significantly greater risk of endometriosis, new research shows. br / iReuters Health Information/i
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Canadian researchers describe a novel autologous transplant protocol in 2 patients who have recovered normal function. br / iMedscape Medical News/i
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The AMA has said that scheduled outages for the Open Payments Web site are further proof that the system is not ready for prime time. br / iMedscape Medical News/i
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Participating in divided-attention training programs can increase activation of the brain region involved in multitasking in healthy adults, which may help reduce the risk for cognitive decline. br / iMedscape Medical News/i
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BioCryst Pharmaceuticals Inc said it expects to initiate a study within weeks to test its antiviral in primates for use against Ebola infections. br / iReuters Health Information/i
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